Pre-ISA
Amos Manor was born in 1918 in Transylvania, Romania as Arthur Mendelovitz. He immigrated to Israel in 1949 and less than a month later, began to work in the ISA. Following the outbreak of World War II, he was drafted to the Hungarian Army, but in 1944 was transferred to the Auschwitz concentration camp. Prior to his immigration to Israel, he served as the secretary of the Bucharest, Romania branch of the Aliyah Bet for clandestine immigration to Israel, under the alias "Amos", which he later adopted as his first name.

In the ISA
1949 - appointed department head in the division for non-Arab affairs, and became the first department director for Eastern Europe.

1950 - appointed unit head within the division for non-Arab affairs.

1952 - appointed Deputy ISA Director

1953 - appointed ISA Director

1964 - retired from the ISA.

Post-retirement
Following his service in the ISA, and until he passed away, Manor worked for a Swiss investment company active in Israel, as a consultant to various companies, and served as director of a number of companies. He was the chairman of the board of directors of a number of banks and of the stock exchange and was also a partner in the Atlas company for hotel management.

Amos Manor passed away in 2007 at the age of 89.